Women really DO have a better sense of smell than men: Study finds female brain has almost 50% more olfactory cells

Researchers have solved the mystery of why women have a better sense of smell than men - and say it is all down to their brain.  

Males and females greatly differ in their perceptual evaluation of odours, with women outperforming men on many kinds of smell tests.

However, until now researchers have not known why.

HOW THEY DID IT

The group examined post-mortem brains from seven men and 11 women who were all over the age of 55 at the time of death. 

All individuals were neurologically healthy and none worked in professions requiring exceptional olfactory abilities, such as coffee-tasting or professional cooking. 

By calculating the number of cells in the olfactory bulbs of these individuals, the group (that also included researchers from the University of São Paulo, the University of California, San Francisco, and the Albert Einstein Hospital in São Paulo) discovered that women have on average 43% more cells than men in this brain structure. 

Professor Roberto Lent from the Institute of Biomedical Sciences at the Federal University of Rio de Janeiro and the National Institute of Translational Neuroscience, Ministry of Science and Technology in Brazil, has finally found biological evidence in the brains of men and women that may explain the olfactory difference between genders.

Sex differences in olfactory detection may play a role in differentiated social behaviors and may be connected to one's perception of smell, which is naturally linked to associated experiences and emotions, the researchers say.

This led them to believe women's olfactory superiority was cognitive or emotional, rather than perceptual.

Previous studies investigating the biological roots of greater olfactory sensitivity in women have used imaging methods that allow gross measures of brain structures. 

Researchers used a machine called an isotropic fractionator, a fast and reliable technique previously developed by a group of researchers at Federal University of Rio de Janeiro.

It measures the absolute number of cells in a given brain structure such as the olfactory bulb, which is the first brain region to receive olfactory information captured by the nostrils.

The group examined post-mortem brains from seven men and 11 women who were all over the age of 55 at the time of death. 

All individuals were neurologically healthy and none worked in professions requiring exceptional olfactory abilities, such as coffee-tasting or professional cooking. 

The find shows thant men and women really do smell differently

The olfactory bulb, which is the first brain region to receive olfactory information captured by the nostrils.

By calculating the number of cells in the olfactory bulbs of these individuals, the group (that also included researchers from the University of São Paulo, the University of California, San Francisco, and the Albert Einstein Hospital in São Paulo) discovered that women have on average 43% more cells than men in this brain structure. 

Counting neurons specifically, the difference reached almost 50% more in women than men.

The question remains whether this higher cell number accounts for the differences in olfactory sensitivity between sexes. 

'Generally speaking, says Prof. Lent, larger brains with larger numbers of neurons correlate with the functional complexity provided by these brains. 

'Thus, it makes sense to think that more neurons in the female olfactory bulbs would provide women with higher olfactory sensitivity'.

The fact that few cells are added to our brains throughout life suggests that women are already born with these extra cells. 

Some believe this olfactory ability is essential for reproductive behaviors such as pair bonding and kin recognition.

If this holds true, then superior olfactory ability is an essential trait that has been inherited and then maintained throughout evolution, an idea expressed by Romanian playwright Eugene Ionesco when he said 'a nose that can see is worth two that sniff'.